Maternal and cord blood cyclophilin A in severe preeclampsia and normal pregnancy and its correlation with vitamin D and zinc
| Autor: | Natasya Prameswari, Riyan Hari Kurniawan, Rima Irwinda, Noroyono Wibowo |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
medicine.medical_specialty chemistry.chemical_element Cypa Zinc 030204 cardiovascular system & hematology Normal pregnancy Correlation Young Adult 03 medical and health sciences Cyclophilin A 0302 clinical medicine Pre-Eclampsia Pregnancy Internal medicine Internal Medicine medicine Vitamin D and neurology Humans Vitamin D 030219 obstetrics & reproductive medicine biology business.industry Obstetrics Obstetrics and Gynecology Fetal Blood biology.organism_classification Severe preeclampsia Cross-Sectional Studies Endocrinology chemistry Cord blood Female business |
| Zdroj: | Hypertension in Pregnancy. 36:283-287 |
| ISSN: | 1525-6065 1064-1955 |
| DOI: | 10.1080/10641955.2017.1385792 |
| Popis: | Objective: To investigate maternal and cord blood cyclophilin A level in severe preeclampsia compared with normal pregnancy and its correlation with vitamin D and zinc level.Methods: We conducted a cross-sectional observational study of pregnant women who gave birth in Cipto Mangunkusumo Hospital between January and April 2014.Results: Thirty-nine subjects were included. Subjects with severe preeclampsia have higher serum cyclophilin A levels compared with normotensive pregnancy (1299.60 vs. 1039.50; p 0.017). Maternal cyclophilin A, vitamin D, and zinc correlation were not statistically significant (p 0.189 & p 0.853).Conclusion: Cyclophilin A levels in severe preeclampsia is higher compared to normal pregnancy. There is no correlation between cyclophilin A, zinc, and vitamin D. |
| Databáze: | OpenAIRE |
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