DNA fingerprinting by hybridisation to oligonucleotide arrays
| Autor: | E. M. Southern |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Molecular Sequence Data
Clinical Biochemistry Oligonucleotides Computational biology Biology Biochemistry DNA sequencing Analytical Chemistry Automation chemistry.chemical_compound Sequence Homology Nucleic Acid Animals Humans Oligonucleotide Arrays Genetics Gel electrophoresis Base Sequence Oligonucleotide Solid surface Nucleic Acid Hybridization Forensic Medicine Biological Evolution DNA Fingerprinting chemistry DNA profiling DNA |
| Zdroj: | Electrophoresis. 16:1539-1542 |
| ISSN: | 1522-2683 0173-0835 |
| DOI: | 10.1002/elps.11501601256 |
| Popis: | Most methods for analysing variation in DNA sequences rely on gel electrophoresis, a method which is difficult to automate and to quantify. Hybridisation to oligonucleotides bound to a solid surface offers alternatives, with the advantage that they can be more readily automated and lend themselves to powerful statistical analytical procedures. In this paper, we discuss a number of different ways in which oligonucleotide arrays could be used for DNA typing for applications in forensic science. |
| Databáze: | OpenAIRE |
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