Effect of Alrestatin on Arginine-Induced Secretion of Glucagon and Insulin in the Rat
| Autor: | M. Kobric, W. Lippmann |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Male
medicine.medical_specialty Arginine Endocrinology Diabetes and Metabolism medicine.medical_treatment Clinical Biochemistry Biochemistry Glucagon chemistry.chemical_compound Endocrinology Cataracts Aldehyde Reductase Internal medicine Diabetes mellitus Insulin Secretion Lens Crystalline medicine Animals Insulin Secretion Chemistry Biochemistry (medical) General Medicine Isoquinolines medicine.disease Aldose reductase inhibitor Rats Alrestatin Sugar Alcohol Dehydrogenases medicine.drug |
| Zdroj: | Hormone and Metabolic Research. 10:280-282 |
| ISSN: | 1439-4286 0018-5043 |
| DOI: | 10.1055/s-0028-1093414 |
| Popis: | Alrestatin, a lens aldose reductase inhibitor, decreased i.v. arginine-induced glucagon levels and augmented arginine-stimulated insulin release in the ether anesthetized rat. Alrestatin may then be useful in the treatment of diabetes mellitus, due to its actions on insulin and glucagon, and its capacity to delay the onset of sugar-induced cataracts in the rat. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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