Comparison of Septic Shock Due to Gram-Negative and Gram-Positive Organisms
| Autor: | Clarence A. Guenter, Lerner B. Hinshaw |
|---|---|
| Rok vydání: | 1970 |
| Předmět: |
Male
Cardiac output Bicarbonate Blood Pressure Blood volume Biology General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Oxygen Consumption Heart Rate medicine Animals Cardiac Output Respiratory system Escherichia coli Infections Septic shock Respiration Haplorhini Carbon Dioxide Staphylococcal Infections medicine.disease Shock Septic Oxygen tension Oxygen Disease Models Animal Blood pressure chemistry Anesthesia Immunology Female Vascular Resistance Respiratory minute volume |
| Zdroj: | Experimental Biology and Medicine. 134:780-783 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-134-34882 |
| Popis: | Cardiorespiratory effects of gram-negative and gram-positive septicemia were compared in the lightly anesthetized rhesus monkey. Thirty to 60 minutes after the onset of infusion of organisms, the cardiac output was higher and the peripheral resistance lower in the group that received staphylocci, as compared to the group that received E. coli. Subsequently, the cardiac output decreased, systemic pressure decreased, minute ventilation increased, alveolo-arterial oxygen tension gradients increased and arterial PCO2 and bicarbonate decreased as previously described in septic shock and to a comparable degree in both groups. These findings suggest a common host response to gram-positive and gram-negative organisms. (Author) |
| Databáze: | OpenAIRE |
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