Dialysis dose and risk factors for death among ESRD patients treated with twice-weekly hemodialysis: a prospective cohort study
| Autor: | Thanachai Panaput, Somnuek Domrongkitchaiporn, Cholatip Pongskul, Dhavee Sirivongs, Surapong Narenpitak, Kannika Niwattayakul, Ammrit Suwattanasin, Sajja Tatiyanupanwong, Pisith Intarawongchot, Thathsalang Keobounma, Sirirat Anutrakulchai, Bandit Thinkhamrop, Pakorn Tungkasereerak, Chavasak Kanokkantapong, Laksamon Praderm, Jirasak Anukulanantachai |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Hepatitis Viral Human medicine.medical_treatment Comorbidity Kaplan-Meier Estimate Diabetes Complications Young Adult Renal Dialysis Risk Factors Internal medicine medicine Humans Dosing Prospective Studies Young adult Intensive care medicine Prospective cohort study Dialysis Serum Albumin Aged Proportional Hazards Models Hepatitis Aged 80 and over Proportional hazards model business.industry Smoking Age Factors Hematology General Medicine Middle Aged medicine.disease Prognosis Thailand Hospitalization Nephrology Cardiovascular Diseases Kidney Failure Chronic Female Hemodialysis business Hypoalbuminemia |
| Zdroj: | Blood purification. 38(3-4) |
| ISSN: | 1421-9735 |
| Popis: | Background/Aims: We aimed to define the dosing and risk factors for death in patients undergoing twice-weekly hemodialysis. Methods: A prospective multi-center cohort study was conducted with one-year observation. Patients treated with twice- or thrice-weekly hemodialysis were identified. Death and first admission were the outcomes. spKt/V was a factor of interest. Results: We enrolled 504 twice-weekly and 169 thrice-weekly hemodialysis patients. The mean weekly values of spKt/V in the two groups were 3.4 and 5.1. The one-year survival rate and times to hospitalization were similar in both groups. The hazard ratios for death in higher spKt/V quartile was not associated with lower mortality, p = 0.70. The four significant predictors for death were serum albumin, HR = 2.6, current smoking, HR = 19.3, age, HR = 1.1, and the Index of Coexistent Disease [ICED], HR = 1.9. Conclusion: The effect of spKt/V on short-term mortality was not obvious in twice-weekly dialysis patients. Attention should be paid to patients who smoke, have hypoalbuminemia, are elderly, or have a high ICED. |
| Databáze: | OpenAIRE |
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