L-ascorbic acid and the evolution of multicellular eukaryotes
| Autor: | John A. Edgar |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Statistics and Probability Ascorbic Acid General Biochemistry Genetics and Molecular Biology Evolution Molecular 03 medical and health sciences 0302 clinical medicine Meiosis Organelle Photosynthesis General Immunology and Microbiology biology Applied Mathematics General Medicine Plants biology.organism_classification Ascorbic acid Aerobiosis Multicellular organism Eukaryotic Cells 030104 developmental biology Evolutionary biology Modeling and Simulation Eukaryote General Agricultural and Biological Sciences 030217 neurology & neurosurgery Bacteria Archaea |
| Zdroj: | Journal of Theoretical Biology. 476:62-73 |
| ISSN: | 0022-5193 |
| DOI: | 10.1016/j.jtbi.2019.06.001 |
| Popis: | The lifeless earth was formed around 4.5 billion years ago and the first anaerobic unicellular “organisms” may have appeared half a billion years later. Despite subsequent prokaryotes (bacteria and archaea) evolving quite complex biochemistry and some eukaryote characteristics, the transition from unicellular prokaryotes to multicellular, aerobic eukaryotes took a further 2.5 billion years to begin. The key factor or factors that eventually caused this long-delayed transition is a question that has been a focus of considerable research and a topic of discussion over many years. On the basis of the extensive literature available and consideration of some of the characteristics that distinguish multicellular eukaryotes from prokaryotes, it is proposed that, as well as the development of oxygenic photosynthesis producing high levels of environmental oxygen and the formation of vital organelles such as aerobic adenosine triphosphate-generating mitochondria, the concurrent evolution of the L-ascorbic acid redox system should be considered as a key factor that led to the evolution of multicellular eukaryotes and it remains vitally involved in the maintenance of multicellularity and many other eukaryote characteristics. |
| Databáze: | OpenAIRE |
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