Recombinant Factor VIIa for the Prophylaxis of Perioperative Hemorrhage in a Patient With Congenital Factor XI Deficiency Undergoing Brain Tumor Neurosurgery

Autor: Michael Sabel, Ruediger E. Scharf, Rainer B. Zotz, Christoph Sucker, Walter Stummer, Andrea Gerhardt
Rok vydání: 2007
Předmět:
Zdroj: Clinical and Applied Thrombosis/Hemostasis. 14:472-475
ISSN: 1938-2723
1076-0296
DOI: 10.1177/1076029607305119
Popis: The authors report on the first successful use of recombinant activated factor VII for the prophylaxis of bleeding during brain tumor neurosurgery in a patient suffering from inherited factor XI deficiency. Using the agent, surgery was performed without any bleeding complications. In this setting, off-label use of recombinant activated factor VII appears to be a promising alternative for patients suffering from this rare hemostatic defect with hitherto limited therapeutic options.
Databáze: OpenAIRE
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