Review of Diagnostic Tests for Detection of
Autor: | Konstantin P. Lyashchenko, Sven D.C. Parsons, Charlene Clarke, Katrin Smith, Robin M. Warren, Michele A. Miller, Taschnica T Sylvester, David Cooper, Candice R. de Waal, Anzaan Dippenaar, Wynand J. Goosen, Christina Meiring, Paul D. van Helden, Léanie Kleynhans, Tanya J. Kerr, Peter Buss, Samantha Goldswain, Rachiel Gumbo, Eduard O. Roos, Netanya Bernitz, Roxanne L. Higgitt, Josephine Chileshe |
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Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Tuberculosis 040301 veterinary sciences Wildlife Zoology Review Disease immunological assays direct detection of mycobacteria 0403 veterinary science 03 medical and health sciences diagnostics Bovine tuberculosis medicine South African wildlife bovine tuberculosis Mycobacterium bovis gene expression assays lcsh:Veterinary medicine biology General Veterinary business.industry Diagnostic test 04 agricultural and veterinary sciences medicine.disease biology.organism_classification cytokine release assays 030104 developmental biology lcsh:SF600-1100 Veterinary Science Livestock Identification (biology) business |
Zdroj: | Frontiers in Veterinary Science, Vol 8 (2021) Frontiers in Veterinary Science |
ISSN: | 2297-1769 |
Popis: | Wildlife tuberculosis is a major economic and conservation concern globally. Bovine tuberculosis (bTB), caused byMycobacterium bovis(M. bovis), is the most common form of wildlife tuberculosis. In South Africa, to date,M. bovisinfection has been detected in 24 mammalian wildlife species. The identification ofM. bovisinfection in wildlife species is essential to limit the spread and to control the disease in these populations, sympatric wildlife species and neighboring livestock. The detection ofM. bovis-infected individuals is challenging as only severely diseased animals show clinical disease manifestations and diagnostic tools to identify infection are limited. The emergence of novel reagents and technologies to identifyM. bovisinfection in wildlife species are instrumental in improving the diagnosis and control of bTB. This review provides an update on the diagnostic tools to detectM. bovisinfection in South African wildlife but may be a useful guide for other wildlife species. |
Databáze: | OpenAIRE |
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