Glioblastoma Multiforme and Ascending Weakness

Autor: Lara Cooke, Werner J. Becker, William Morrish
Rok vydání: 2002
Předmět:
Zdroj: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 29:372-374
ISSN: 2057-0155
0317-1671
Popis: An 18-year-old man with a known glioblastoma multiforme, previously treated with de-bulking, chemotherapy, radiation and steroids, underwent a repeat craniotomy after presenting with several days of intractable vomiting and headache. Postoperatively, he developed progressive delirium, bilateral sixth and seventh nerve palsies, dysphagia and ascending weakness of the upper and lower limbs. Within five postoperative days, he was quadraparetic, areflexic and had marked extraocular muscle and facial weakness, dysphagia, dysphonia and respiratory muscle weakness. The patient was started empirically on intravenous immunoglobulin for suspected Guillain-Barré syndrome (GBS). The following day, lumbar puncture demonstrated elevated protein (1.96g/l; normal
Databáze: OpenAIRE