Periodontitis is associated with angiographically verified coronary artery disease
Autor: | Susanna Paju, Pirkko J. Pussinen, Päivi Mäntylä, Jaakko Peltola, Juha Sinisalo, Markku S. Nieminen, Kåre Buhlin |
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Rok vydání: | 2011 |
Předmět: |
Male
medicine.medical_specialty Acute coronary syndrome Periodontal examination Bleeding on probing Alveolar Bone Loss 030204 cardiovascular system & hematology Coronary Angiography Statistics Nonparametric Coronary artery disease Tooth Loss 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Humans Medicine Periodontal Probing Myocardial infarction Finland Dental alveolus Aged Periodontitis Analysis of Variance Chi-Square Distribution business.industry Smoking Coronary Stenosis 030206 dentistry Middle Aged Atherosclerosis medicine.disease 3. Good health Chronic Periodontitis Cardiology Regression Analysis Periodontics Female medicine.symptom business |
Zdroj: | Journal of Clinical Periodontology. 38:1007-1014 |
ISSN: | 0303-6979 |
Popis: | INTRODUCTION We investigated the association of periodontitis and severity of coronary artery disease (CAD) as verified using coronary angiography. MATERIAL AND METHODS Participants were recruited among those attending coronary angiography at Helsinki University Central Hospital, Finland, in 2007 and 2008. Detailed clinical periodontal examination [number of teeth, bleeding on probing, periodontal probing depth (PPD)] and oral panoramic radiographs [alveolar bone loss (ABL), angular bone defects] were performed. RESULTS Of 506 patients, 123 (24.3%) had no significant CAD, whereas 184 (36.4%) had stable CAD and 169 (33.4%) acute coronary syndrome (ACS). Both stable CAD and ACS were associated with 8-17 missing teeth with ORs 4.33 (1.61-11.7, p = 0.020) and 5.24 (1.90-14.5, p = 0.014), and more than seven teeth with PPD ≥6 mm with ORs 2.44 (1.01-6.07, p = 0.049) and 2.75 (1.16-6.53, p = 0.022) respectively. Severe ABL was associated with ACS with an OR 5.39 (1.23-23.6, p = 0.025). Number of stenosed arteries was linearly associated with ABL (p for trend |
Databáze: | OpenAIRE |
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