Isolated Splenic Metastases of Her2+++ Gastroesophageal Junction Adenocarcinoma
| Autor: | Slimane Dermeche, Camille Bazin, Pauline Ries, Jacques Ewald, Flora Poizat, Julie Sigrand, Jérôme Guiramand, Jean-Luc Raoul |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Spleen Isolated splenic metastases Gastroesophageal Junction Adenocarcinoma Splenic artery lcsh:RC254-282 Gastroenterology Contractility 03 medical and health sciences Gastric adenocarcinoma 0302 clinical medicine Immune system Her2 Internal medicine medicine.artery medicine business.industry Cancer lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease digestive system diseases medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Adenocarcinoma Published online: March 2016 030211 gastroenterology & hepatology business |
| Zdroj: | Case Reports in Oncology Case Reports in Oncology, Vol 9, Iss 1, Pp 154-157 (2016) |
| ISSN: | 1662-6575 |
| Popis: | Isolated metastases from gastric adenocarcinoma to the spleen are very infrequent. Usually, there are multiple metastases from gastric cancer, and isolated splenic metastases are very rare [Lam and Tang: Arch Pathol Lab Med 2000;124:526-530] because of certain anatomical and physiological characteristics (e.g., angulation between the splenic artery and celiac trunk, paucity of afferent lymph flow toward the spleen, contractility of the spleen and major immune content). Here, we report 2 cases of isolated splenic metastases from an adenocarcinoma of the gastroesophageal junction, both with long-term survival outcome and overexpression of Her2. |
| Databáze: | OpenAIRE |
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