Role of eHealth application Oncokompas in supporting self-management of symptoms and health-related quality of life in cancer survivors: a randomised, controlled trial
| Autor: | Simone E. J. Eerenstein, Irma M. Verdonck-de Leeuw, Dirkje W. Sommeijer, Karen Holtmaat, Robert J. Baatenburg de Jong, Michiel W. M. van den Brekel, Patricia Jansen, Femke Jansen, Koen de Heer, C. René Leemans, Jose A. Hardillo, Birgit I. Lissenberg-Witte, Grard A. P. Nieuwenhuijzen, Robert P. Takes, Wim T. van den Broek, Josée M. Zijlstra, Ilse Houtenbos, Japke F. Petersen, Cees G. Schaar, Matthijs Westerman, Robert Jan E. Sedee, Koop Bosscha, Nicolette L. Tiren-Verbeet, Lonneke V. van de Poll-Franse, Jimmie Honings, Anja van der Hout, Cornelia F. van Uden-Kraan, Pim Cuijpers, Remco de Bree |
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| Přispěvatelé: | Oncology, Graduate School, Clinical Psychology, APH - Mental Health, World Health Organization (WHO) Collaborating Center, APH - Global Health, Clinical, Neuro- & Developmental Psychology, Otolaryngology / Head & Neck Surgery, VU University medical center, CCA - Cancer Treatment and quality of life, Hematology, APH - Personalized Medicine, Otorhinolaryngology and Head and Neck Surgery, Medical and Clinical Psychology |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty 020205 medical informatics 02 engineering and technology law.invention 03 medical and health sciences All institutes and research themes of the Radboud University Medical Center 0302 clinical medicine Breast cancer Cancer Survivors Quality of life Randomized controlled trial SDG 3 - Good Health and Well-being law Neoplasms Surveys and Questionnaires 0202 electrical engineering electronic engineering information engineering eHealth Humans Medicine Patient Reported Outcome Measures Aged Self-management business.industry Self-Management Head and neck cancer Cancer Middle Aged Prognosis medicine.disease Telemedicine Cancer registry Survival Rate Oncology 030220 oncology & carcinogenesis Quality of Life Physical therapy Female business Follow-Up Studies Rare cancers Radboud Institute for Health Sciences [Radboudumc 9] |
| Zdroj: | Lancet Oncology, 21, 80-94 Lancet Oncology, 21, 1, pp. 80-94 lancet oncology, 21(1), 80-94. Lancet Publishing Group The Lancet Oncology, 21(1), 80-94. Lancet Publishing Group van der Hout, A, van Uden-Kraan, C F, Holtmaat, K, Jansen, F, Lissenberg-Witte, B I, Nieuwenhuijzen, G A P, Hardillo, J A, Baatenburg de Jong, R J, Tiren-Verbeet, N L, Sommeijer, D W, de Heer, K, Schaar, C G, Sedee, R J E, Bosscha, K, van den Brekel, M W M, Petersen, J F, Westerman, M, Honings, J, Takes, R P, Houtenbos, I, van den Broek, W T, de Bree, R, Jansen, P, Eerenstein, S E J, Leemans, C R, Zijlstra, J M, Cuijpers, P, van de Poll-Franse, L V & Verdonck-de Leeuw, I M 2020, ' Role of eHealth application Oncokompas in supporting self-management of symptoms and health-related quality of life in cancer survivors : a randomised, controlled trial ', The Lancet Oncology, vol. 21, no. 1, pp. 80-94 . https://doi.org/10.1016/S1470-2045(19)30675-8 Lancet Oncology, 21(1), 80-94. Lancet Publishing Group LANCET ONCOLOGY, 21(1), 80. Lancet Publishing Group |
| ISSN: | 1470-2045 |
| Popis: | Background: Knowledge about the efficacy of behavioural intervention technologies that can be used by cancer survivors independently from a health-care provider is scarce. We aimed to assess the efficacy, reach, and usage of Oncokompas, a web-based eHealth application that supports survivors in self-management by monitoring health-related quality of life (HRQOL) and cancer-generic and tumour-specific symptoms and obtaining tailored feedback with a personalised overview of supportive care options. Methods: In this non-blinded, randomised, controlled trial, we recruited patients treated at 14 hospitals in the Netherlands for head and neck cancer, colorectal cancer, breast cancer, Hodgkin lymphoma, or non-Hodgkin lymphoma. Adult survivors (aged ≥18 years) were recruited through the Netherlands Cancer Registry (NCR) and invited by their treating physician through the Patient Reported Outcomes Following Initial Treatment and Long term Evaluation of Survivorship (PROFILES) registry. Participants were randomly assigned (1:1) by an independent researcher to the intervention group (access to Oncokompas) or control group (access to Oncokompas after 6 months), by use of block randomisation (block length of 68), stratified by tumour type. The primary outcome was patient activation (knowledge, skills, and confidence for self-management), assessed at baseline, post-intervention, and 3-month and 6-month follow-up. Linear mixed models (intention-to-treat) were used to assess group differences over time from baseline to 6-month follow-up. The trial is registered in the Netherlands Trial Register, NTR5774 and is completed. Findings: Between Oct 12, 2016, and May 24, 2018, 625 (21%) of 2953 survivors assessed for eligibility were recruited and randomly assigned to the intervention (320) or control group (305). Median follow-up was 6 months (IQR 6−6). Patient activation was not significantly different between intervention and control group over time (difference at 6-month follow-up 1·7 [95% CI −0·8–4·1], p=0·41). Interpretation: Oncokompas did not improve the amount of knowledge, skills, and confidence for self-management in cancer survivors. This study contributes to the evidence for the development of tailored strategies for development and implementation of behavioural intervention technologies among cancer survivors. Funding: Dutch Cancer Society (KWF Kankerbestrijding). |
| Databáze: | OpenAIRE |
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