| Autor: |
Aobulikasimu Hasan, Meng Zhang, Zhan-Peng Shang, Yang Yi, Yi Kuang, Rong Yu, Jing-Jing Fan, Yu-Xi Huang, Dilaram Nijat, Xue Qiao, Min Ye |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Phytochemistry. 201:113284 |
| ISSN: |
0031-9422 |
| Popis: |
In this work, a bioassay-guided fractionation strategy was used to isolate 26 phenolic compounds from the ethyl acetate partition of an ethanol extract of the aerial parts of Glycyrrhiza uralensis Fisch. ex DC. Among them, 8 prenylated phenolic compounds (glycyuralins Q-X) were described for the first time. The two enantiomers of glycyuralin Q were purified and their absolute configurations were established by ECD spectral calculations. (1″R, 2″S)-glycyuralin Q and (1″S, 2″R)-glycyuralin Q showed significant inhibitory activities against SARS-CoV-2 virus proteases 3CL |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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