Mucoepidermoid Carcinoma Associated with Osteosarcoma in a True Malignant Mixed Tumor of the Submandibular Region
Autor: | Marco de Vincentiis, Bruna Cerbelli, Dario Marcotullio, Giannicola Iannella, Giuseppe Magliulo |
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Jazyk: | angličtina |
Rok vydání: | 2015 |
Předmět: |
Pathology
medicine.medical_specialty salivary gland Case Report Pleomorphic adenoma stomatognathic system Mucoepidermoid carcinoma Carcinosarcoma medicine Mixed tumor Salivary gland business.industry mucoepidermoid carcinoma true malignant mixed tumor submandibular gland General Medicine lcsh:Otorhinolaryngology medicine.disease lcsh:RF1-547 Submandibular gland Malignant mixed tumor stomatognathic diseases medicine.anatomical_structure Osteosarcoma business |
Zdroj: | Case Reports in Otolaryngology Case Reports in Otolaryngology, Vol 2015 (2015) |
ISSN: | 2090-6773 2090-6765 |
Popis: | Introduction. True malignant mixed tumor, also known as carcinosarcoma, is a rare tumor of the salivary gland composed of both malignant epithelial and malignant mesenchymal elements. Frequently carcinosarcoma arises in the background of a preexisting pleomorphic adenoma; however, if no evidence of benign mixed tumor is present, the lesion is known as carcinosarcoma “de novo.” We reported the first case of true malignant mixed tumor of the submandibular gland composed of high grade mucoepidermoid carcinoma associated with osteosarcoma.Case Presentation. A 69-year-old Caucasian male came to our department complaining of the appearance of an asymptomatic left submandibular neoformation progressively increasing in size over 3 months. We opted for surgical treatment. Histological examination confirmed the diagnosis of carcinosarcoma with the coexistence of high grade mucoepidermoid carcinoma and osteosarcoma.Conclusion. To the best of our knowledge, in the true malignant mixed tumor of the submandibular gland, mucoepidermoid carcinoma associated with osteosarcoma has never been previously reported. |
Databáze: | OpenAIRE |
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