Dysregulation of Airway Cytokine Expression in Chronic Obstructive Pulmonary Disease and Asthma
| Autor: | Eugene R. Bleeker, Jeffrey D. Hasday, Kimberly A. McCrea, Susan S. Meltzer |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Pulmonary and Respiratory Medicine
COPD business.industry Smoking Cytokine expression Pulmonary disease Bronchi Host factors Disease Critical Care and Intensive Care Medicine medicine.disease Asthma respiratory tract diseases Gene Expression Regulation Cigarette smoking Immunology Cytokines Humans Medicine Lung Diseases Obstructive business Airway Bronchoalveolar Lavage Fluid |
| Zdroj: | American Journal of Respiratory and Critical Care Medicine. 150:S54-S58 |
| ISSN: | 1535-4970 1073-449X |
| DOI: | 10.1164/ajrccm/150.5_pt_2.s54 |
| Popis: | Cigarette smoking is the major factor responsible for chronic obstructive pulmonary disease (COPD). COPD occurs in a minority of smokers, but the host factors that modify risk of disease have not been clearly elucidated. There is significant clinical and histopathologic overlap between COPD and asthma, including the accumulation and activation of airway inflammatory cells. These two disorders are compared and contrasted. Abnormal airway inflammatory cytokine expression in these disorders is discussed. |
| Databáze: | OpenAIRE |
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