Coronary Edema Demonstrated by Cardiovascular Magnetic Resonance in Patients With Peri-Stent Inflammation and Aneurysm Formation After Treatment by Drug-Eluting Stents
| Autor: | Jens Flensted Lassen, Leif Thuesen, Michael Maeng, Evald Høj Christiansen, Shengxian Tu, Erling Falk, Won Yong Kim, Samuel A. Thrysøe, Søren Høyer, Per Hostrup Nielsen, Hans Erik Bøtker, Niels Ramsing Holm |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Inflammation Coronary Angiography Prosthesis Design Percutaneous Coronary Intervention Coronary thrombosis Restenosis Predictive Value of Tests Internal medicine Edema Medicine Humans magnetic resonance imaging Radiology Nuclear Medicine and imaging cardiovascular diseases stent thrombosis Edema Cardiac optical coherence tomography medicine.diagnostic_test business.industry Coronary Thrombosis Coronary Aneurysm Percutaneous coronary intervention Stent Magnetic resonance imaging Drug-Eluting Stents Middle Aged equipment and supplies medicine.disease Treatment Outcome Predictive value of tests Cardiology Female Radiology medicine.symptom Cardiology and Cardiovascular Medicine business Tomography Optical Coherence |
| Zdroj: | Holm, N R, Kim, W Y, Maeng, M, Thrysøe, S A, Bøtker, H E, Thuesen, L, Høyer, S, Tu, S, Falk, E, Lassen, J F, Nielsen, P H & Christiansen, E H 2013, ' Coronary edema demonstrated by cardiovascular magnetic resonance in patients with peri-stent inflammation and aneurysm formation after treatment by drug-eluting stents ', Circulation. Cardiovascular Imaging (Online), vol. 6, no. 2, pp. 352-4 . https://doi.org/10.1161/CIRCIMAGING.112.979997 Circulation: Cardiovascular Imaging, 6(2), 352-354 |
| DOI: | 10.1161/CIRCIMAGING.112.979997 |
| Popis: | Drug-eluting stents (DES) minimized the occurrence of in-stent restenosis but with a penalty of increased risk of late stent thrombosis.1 In patients with late stent thrombosis, adverse vessel wall reactions such as uncovered and malapposed stent struts, coronary aneurysms, and accelerated neoatherosclerosis2 have been identified. The stent polymer is suspected to induce an inflammatory response,3 resulting in vessel wall abnormalities. Identification of patients with an inflammatory response to DES might be essential in preventing late stent thrombosis. Inflammatory processes increase vessel wall permeability, leading to edema, and both native and peri-stent vessel wall inflammation may be associated with tissue edema. Cardiovascular magnetic resonance (CMR) performed with a T2-weighted short-τ inversion recovery sequence (T2-STIR) has recently been shown to identify localized coronary edema in the culprit artery of patients with acute myocardial infarction.4 Parameters for the ECG-triggered, navigator-gated, dark-blood, T2-STIR fast-spin-echo sequence were as follows: repetition time, 2 RR intervals; echo time, 100 milliseconds; echo train length, twenty 0.68×0.68×8-mm3 voxels; and 2 signal averages. Here we present 3 patients treated with DES (Cypher Select+, Cordis, Johnson & Johnson, Miami Lakes, FL) who demonstrate peri-stent edema as a possible marker of stent-induced coronary inflammation. A 41-year-old woman experienced very late stent thrombosis 15 months after treatment with DES in the proximal left anterior descending … |
| Databáze: | OpenAIRE |
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