Molecular identification of Coccidioides immitis in formalin-fixed, paraffin-embedded (FFPE) tissues from a Colombian patient
| Autor: | Roberto Suárez-Alvarez, O Ángela Tobón, H Alejandro Vélez, Cristina Elena Canteros, A María del Pilar Jimenez, Adriana Toranzo, M. Angela Restrepo |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Tissue Fixation Formalin fixed paraffin embedded Patients Coccidioides immitis Biopsy Biology Colombia DNA sequencing Formaldehyde medicine Humans Pathology Molecular Mycosis Molecular identification Coccidioidomycosis Geographic area Coccidioides General Medicine Middle Aged medicine.disease biology.organism_classification Virology Fungal disease Infectious Diseases Molecular Diagnostic Techniques Paraffin Geographic regions |
| Zdroj: | Medical mycology. 53(5) |
| ISSN: | 1460-2709 |
| Popis: | Coccidioides immitis and C. posadasii are the etiologic agents of coccidioidomycosis, an endemic fungal disease of the Americas. In Colombia, this mycosis is uncommon, and only five cases, two of them imported, have been documented.By means of DNA sequencing, C. immitis was identified in formalin-fixed, paraffin-embedded archival tissues samples from the 5th Colombian patient diagnosed in 1997. The patient was born in Pinto, Department of Magdalena, and had never visited other geographic regions, a reason to consider that the mycosis had been acquired locally.This species is primarily found in California although it has been occasionally reported in other geographic areas such as Mexico and Brazil. This is the first indigenous report of C. immitis-associated coccidioidomycosis in a Colombian patient. |
| Databáze: | OpenAIRE |
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