Microangiopathy of the brain and retina with hearing loss in a 50 year old woman: extending the spectrum of Susac's syndrome
| Autor: | Roger A. Barker, P Meyer, D J Dick, Neil J Scolding, J R Anderson |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1999 |
| Předmět: |
medicine.medical_specialty
Pediatrics Ataxia Hearing Loss Sensorineural Encephalopathy Short Report Retina Factor V Leiden Medicine Humans Susac's syndrome Susac Syndrome medicine.diagnostic_test business.industry Brain biopsy Brain Cerebral Arteries Middle Aged medicine.disease Magnetic Resonance Imaging Surgery Psychiatry and Mental health Cerebrovascular Disorders Female Neurology (clinical) medicine.symptom business Vasculitis Myoclonus |
| Popis: | A 50 year old woman presented with a subacute onset of vertigo and diplopia followed by an encephalopathy with confusion, spasticity, ataxia, myoclonus, and multiple branch retinal arteriolar occlusions and unilateral sensorineural deafness. Brain biopsy confirmed multiple microinfarcts with no vasculitis. After the procedure she had a right iliofemoral deep vein thrombosis and was found to be heterozygous for the factor V Leiden mutation. She was treated with anticoagulants and made a marked recovery with no relapses 6 months after presentation. This case extends the age range at which Susac's syndrome can present, and raises the possibility that the condition may be associated with abnormalities of coagulation. |
| Databáze: | OpenAIRE |
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