Stereochemistry of Enzymic Citrate Synthesis and Cleavage

Autor:	Helmut Lenz, Peter Wunderwald, Wolfgang Buckel, Gerhard Gottschalk, Hermann Eggerer, John Warcup Cornforth, Richard Mallaby, C. Donninger, John W. Redmond
Rok vydání:	1970
Předmět:	ATP citrate lyase Stereochemistry Citric Acid Cycle Malates Lyases Tritium 010402 general chemistry Cleavage (embryo) 01 natural sciences 03 medical and health sciences chemistry.chemical_compound Fumarates Citrate synthase Glycolysis Citrates Methylene 030304 developmental biology Clostridium 0303 health sciences Multidisciplinary biology Chemistry Stereoisomerism 0104 chemical sciences biology.protein Methyl group
Zdroj:	Nature. 226:517-519
ISSN:	1476-4687 0028-0836
Popis:	By enzymic reactions using and generating asymmetrically labelled acetic acids, it is shown that R and S citrate synthases, citrate lyase and ATP citrate lyase all produce inversion of configuration at the methyl group when citrate is synthesized, or at the methylene group where citrate is cleaved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90557aa012d839a13e19f93c01aacd0 https://doi.org/10.1038/226517a0 Zobrazit plný text záznamu