A Three-Component Reaction for the Synthesis of 1-Azabicyclo[3.1.0]hexane-3-enes

Autor: Mahnaz Saraii, Tadeusz Lis, Bagher Mohammadi, Ali Ramazani, Bakhshali Masoumi, Katarzyna Slepokura, Mahdi Ghorbani, Mojtaba Abbasian
Rok vydání: 2016
Předmět:
Zdroj: Organic letters. 18(19)
ISSN: 1523-7052
Popis: A novel and simple synthesis of 1-azabicyclo[3.1.0]hexane-3-ene derivatives is described. The synthesis is carried out via a simple three-component reaction between aryl aldehydes, malononitrile, and hydroxylamine hydrochloride in water. Eco-friendliness, excellent product yields, short reaction time, inexpensive and readily available starting materials, and interesting reaction and products are the main advantages of this method.
Databáze: OpenAIRE