Synthesis and Reactivity of Mixed Dimethylalkynylaluminum Reagents
| Autor: | Laurent Micouin, Riccardo Piccardi, Serge Turcaud, Erica Benedetti |
|---|---|
| Přispěvatelé: | Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS), Université Paris Descartes - Paris 5 (UPD5)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
010405 organic chemistry
Metalation Chemistry [CHIM.ORGA]Chemical Sciences/Organic chemistry Organic Chemistry 010402 general chemistry Special class 01 natural sciences Combinatorial chemistry Catalysis 0104 chemical sciences Alkynylation Reagent Electrophile [CHIM]Chemical Sciences Reactivity (chemistry) |
| Zdroj: | SYNTHESIS SYNTHESIS, Georg Thieme Verlag, 2018, 51 (01), pp.97-106. ⟨10.1055/s-0037-1610392⟩ |
| ISSN: | 0039-7881 1437-210X |
| Popis: | Organoaluminum derivatives are mostly appreciated for their Lewis acidity properties, but generally not considered as reagents of choice in synthetic transformations involving the creation of C–C bonds. Among these species, dimethylalkynylaluminum reagents represent a special class of compounds, with, in many cases, unique reactivity. This review summarizes the preparation and reactivity of these organometallic reagents with a focus on their synthetic potential.1 Introduction2 Preparation of Dimethylalkynylaluminum Reagents3 Reactivity of Dimethylalkynylaluminum Reagents3.1 Reactions with Csp3 Electrophiles3.2 Reactions with Csp2 Electrophiles4 Transition-Metal-Catalyzed Reactions4.1 Addition to α,β-Unsaturated Enones4.2 Coupling Reactions5 Triple Bond Reactivity6 Conclusion |
| Databáze: | OpenAIRE |
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