Impact of Filter Cigarette Smoking on Lung Cancer Histology
| Autor: | Steven D. Stellman, Ernst L. Wynder, Joshua E. Muscat, Dietrich Hoffmann |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Risk medicine.medical_specialty Pathology Lung Neoplasms Epidemiology Adenocarcinoma Gastroenterology Tobacco smoke Nicotine Age Distribution Internal medicine Humans Medicine Sex Distribution Lung cancer Aged Lung business.industry Smoking Public Health Environmental and Occupational Health Case-control study Cancer Odds ratio Middle Aged medicine.disease United States respiratory tract diseases medicine.anatomical_structure Oncology Case-Control Studies Carcinoma Squamous Cell Female business Filtration medicine.drug |
| Zdroj: | Preventive Medicine. 26:451-456 |
| ISSN: | 0091-7435 |
| DOI: | 10.1006/pmed.1997.0212 |
| Popis: | Background. The rates of lung adenocarcinoma cancer have risen more rapidly than the rates of lung squamous cell cancer over the past 2 decades. Methods. A case‐control study was carried out to assess the impact of long-term filter cigarette smoking on the risk of squamous cell carcinoma (SCC) and adenocarcinoma (AC) of the lung. Results. Odds ratios for SCC among subjects who had smoked only filter cigarettes were reduced relative to lifetime nonfilter cigarette smokers by 30% for men and by 60% for women, but no risk reduction was observed for AC of the lung. Conclusion. The predominance of AC over SCC may be due in part to the fact that smokers of very low yield cigarettes tend to compensate for the lower nicotine levels by inhaling more deeply and frequently, leading to greater exposure of the peripheral lung to the carcinogens in tobacco smoke, and in part to the increased concentration of nitrosamines that preferentially produce AC in laboratory animals. © 1997 Academic |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect