Cytokine Profiles in Periodontitis and COVID-19
| Autor: | Aida Kheiri, Farhad Hajizadeh, Behzad Houshmand, Saber Khazaei, Mehdi Ekhlasmandkermani |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Periodontitis
Respiratory distress business.industry medicine.medical_treatment medicine.disease_cause medicine.disease Chronic periodontitis lcsh:RK1-715 Cytokine covid-19 Infectious disease (medical specialty) lcsh:Dentistry Immunology Genotype cytokine medicine corona virus business Cytokine storm periodontitis General Dentistry Coronavirus |
| Zdroj: | Dental Hypotheses, Vol 12, Iss 1, Pp 36-38 (2021) |
| ISSN: | 2155-8213 |
| DOI: | 10.4103/denthyp.denthyp_161_20 |
| Popis: | Introduction: SARS-CoV-2 is a novel coronavirus that causes an infectious disease named COVID-19. Respiratory distress syndrome and multiple organ failure are the common outcomes of COVID-19 that may finally lead to death. During COVID-19, cytokine storm takes place that is known by the release of notable amounts of pro-inflammatory cytokines including IL-1, IL-6, and TNF-α. The Hypothesis: Periodontal disease are a group of inflammatory diseases in which elevated levels of some cytokine such as IL-1, IL-2, IL-5, IL-6, IL-10, and TNF-α are observed in patients’ serums. Due to the similarity of cytokine expressions in these two diseases, there might be a possible association between COVID-19 and periodontitis, especially the chronic type. Also, genotype polymorphisms of IL-1, IL-6, IL-10, and TNF-α have been proposed to be in association with chronic periodontitis susceptibility. Evaluation of the Hypothesis: assessment of these polymorphisms may also play a significant role in detection of these diseases. |
| Databáze: | OpenAIRE |
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