Pathologic Changes of the Peripheral Vestibular System Secondary to Chronic Otitis Media
| Autor: | Patricia A. Schachern, Sebahattin Cureoglu, Geeyoun Kwon, Michael M. Paparella, Henrique Furlan Pauna, Rafael da Costa Monsanto, Vladimir Tsuprun, Mehmet Erdil |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Adolescent Hair Cells Vestibular 03 medical and health sciences 0302 clinical medicine Utricle Hair Cells Auditory Temporal bone otorhinolaryngologic diseases Humans Medicine 030223 otorhinolaryngology Aged Aged 80 and over Vestibular system business.industry Posterior Semicircular Canal Temporal Bone Anatomy Middle Aged Otitis Media medicine.anatomical_structure Otorhinolaryngology Case-Control Studies Vestibule Chronic Disease Female Surgery Histopathology sense organs Saccule business 030217 neurology & neurosurgery Type II Hair Cell |
| Zdroj: | Otolaryngology–Head and Neck Surgery. 155:494-500 |
| ISSN: | 1097-6817 0194-5998 |
| Popis: | To evaluate the histopathologic changes of dark, transitional, and hair cells of the vestibular system in human temporal bones from patients with chronic otitis media.Comparative human temporal bone study.Otopathology laboratory.To compare the density of vestibular dark, transitional, and hair cells in temporal bones with and without chronic otitis media, we used differential interference contrast microscopy.In the chronic otitis media group (as compared with the age-matched control group), the density of type I and type II hair cells was significantly decreased in the lateral semicircular canal, saccule, and utricle (P.05). The density of type I cells was also significantly decreased in the chronic otitis media group in the posterior semicircular canal (P = .005), but that of type II cells was not (P = .168). The mean number of dark cells was significantly decreased in the chronic otitis media group in the lateral semicircular canal (P = .014) and in the posterior semicircular canal (P = .002). We observed no statistically significant difference in the density of transitional cells between the 2 groups (P.1).The findings of our study suggest that the decrease in the number of vestibular sensory cells and dark cells could be the cause of the clinical symptoms of imbalance of some patients with chronic otitis media. |
| Databáze: | OpenAIRE |
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