Comparison between a differential amperometric detector in the reductive mode and a u.v. detector in high-performance liquid chromatography with vitamin K3 as test compound

Autor:	K. Brunt, D.A. Doornbos, C.H.P. Bruins
Jazyk:	angličtina
Rok vydání:	1981
Předmět:	Detection limit Chromatography Detector Analytical chemistry Linearity Conductivity Biochemistry High-performance liquid chromatography Analytical Chemistry chemistry.chemical_compound Menadione chemistry Linear range Electrode Environmental Chemistry Spectroscopy
Zdroj:	Analytica Chimica Acta, 125, 85-91. ELSEVIER SCIENCE BV
ISSN:	0003-2670
DOI:	10.1016/s0003-2670(01)85052-2
Popis:	The amperometric detector is superior to the u.v. detector in terms of the limit of detection (less than 0.5 ng) and true linearity of response when vitamin K3 (menadione) is used as the test compound with a reversed-phase column. However, the high uncompensated resistance between the reference and working electrodes caused by the low conductivity of the mobile phase, restricts the upper limit of the linear range of the differential amperometric detector to about 200 ng of menadione.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8df7a750a774894345125f046971c77 https://doi.org/10.1016/s0003-2670(01)85052-2 Zobrazit plný text záznamu