Evaluation of blood and tooth element status in asthma cases: a preliminary case–control study
| Autor: | Nagehan Emiralioglu, Suzan Yalçin, S Songül Yalçin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Teeth chemistry.chemical_element Physiology Zinc 010501 environmental sciences 01 natural sciences Article 03 medical and health sciences Diseases of the respiratory system 0302 clinical medicine medicine Deciduous teeth Humans Mass index Magnesium 030212 general & internal medicine Respiratory system Child 0105 earth and related environmental sciences Asthma RC705-779 business.industry Confounding Case-control study Mercury medicine.disease Trace Elements stomatognathic diseases medicine.anatomical_structure Blood chemistry Iron-deficiency anemia Case-Control Studies Multivariate Analysis Female business Tooth Copper |
| Zdroj: | BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-8 (2021) BMC Pulmonary Medicine |
| ISSN: | 1471-2466 |
| Popis: | Background Asthma is a common respiratory disorder; some data were present on the correlation between increased levels of some elements and the risk of asthma development. It was aimed to evaluate the levels of 13 selected blood and tooth elements (magnesium, phosphorus, calcium, chromium, manganese, iron, copper, zinc, strontium, molybdenum, cadmium, lead, mercury) in a well-controlled asthma group and the control group. Methods During the study period, 17 asthma patients and 26 age and gender-matched healthy children donated shed deciduous teeth having neither decay nor filling and enrolled for the study. The element levels in blood and teeth matrixes were analyzed with inductively coupled plasma mass spectrometry. Differences in blood and tooth elements in groups were evaluated with generalized linear models after adjusting confounding factors. Results After adjusting the child’s “z scores of body mass index for age”, history of iron deficiency anemia, and status of parental smoking, the generalized linear model revealed significantly lower tooth magnesium levels, lower blood zinc levels, and lower blood zinc/copper ratio in the asthma group than the control group (p = 0.042, p = 0.034, p = 0.002, respectively). Other studied elements for tooth and blood matrixes were similar in groups. Conclusion Our study revealed some differences in tooth and blood element levels in the asthma group. Further studies on zinc and magnesium levels of severe asthma cases are necessary for the interpretation of the results. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink