Myoclonus Associated with Lorazepam Therapy in Very-Low-Birth-Weight Infants
| Autor: | D. C. Knoppert, H. A. Wong, David S. C. Lee |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Myoclonus
medicine.drug_class Neurological disorder Lorazepam Seizures mental disorders Humans Medicine Involuntary movement business.industry Infant Newborn Infant Low Birth Weight medicine.disease Low birth weight Anesthesia Sedative Recien nacido Injections Intravenous Pediatrics Perinatology and Child Health Female medicine.symptom business Infant Premature Developmental Biology medicine.drug |
| Zdroj: | Neonatology. 66:311-315 |
| ISSN: | 1661-7819 1661-7800 |
| Popis: | Lorazepam is being used with increasing frequency as a sedative in the newborn and the young infant. Concern has been raised with regard to the safety of lorazepam in this age group, especially in very-low-birth-weight (VLBW; < 1,500 g) infants. Three young infants, all of birth weight < 1,500 g, experienced myoclonus following the intravenous administration of lorazepam. The potential neurotoxic effects of the drug (and its vehicle) in this population are discussed. Injectable lorazepam should be used with caution in VLBW infants. |
| Databáze: | OpenAIRE |
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