Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma
| Autor: | Kentaro Yoshinaga, Hideaki Mizoguchi, Shoko Kobayashi, Michihiko Masuda, Masanao Teramura, Koji Iwabe, Toshiko Motoji |
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| Rok vydání: | 2001 |
| Předmět: |
Male
medicine.medical_specialty Naproxen Lymphoma B-Cell Fever Indomethacin Analgesic Gastroenterology Recurrence immune system diseases hemic and lymphatic diseases Internal medicine medicine Humans Antipyretic Aged business.industry Anti-Inflammatory Agents Non-Steroidal Remission Induction Large-cell lymphoma Hematology medicine.disease Lymphoma Surgery Non-Hodgkin's lymphoma Lymph Nodes Lymphoma Large B-Cell Diffuse business Diffuse large B-cell lymphoma Generalized lymphadenopathy medicine.drug |
| Zdroj: | American Journal of Hematology. 66:220-223 |
| ISSN: | 1096-8652 0361-8609 |
| DOI: | 10.1002/1096-8652(200103)66:3<220::aid-ajh1048>3.0.co;2-l |
| Popis: | A 77-year-old man with relapsed non-Hodgkin's lymphoma, diffuse large B-cell type, was treated with naproxen, a nonsteroidal anti-inflammatory drug (NSAID), for paraneoplastic fever. A dramatic disappearance of not only the fever but also generalized lymphadenopathy was observed. Naproxen was continued, and he maintained remission for 10 months. When relapse of lymphoma occurred in spite of continuous naproxen administration, indomethacin, another type of NSAID, was tried. Surprisingly, rapid regression of lymphoma occurred again and was maintained for almost 1 year. These results indicate that NSAIDs are effective in some patients with non-Hodgkin's lymphoma. |
| Databáze: | OpenAIRE |
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