Ventral hernia repair with poly-4-hydroxybutyrate mesh
| Autor: | Amanda Zachem, Daniel L. Davenport, John Scott Roth, Margaret A. Plymale, Adam Dugan |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Hydroxybutyrates Pilot Projects 030230 surgery 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine medicine Humans Mass index Prospective Studies Herniorrhaphy business.industry Perioperative Hepatology Middle Aged Surgical Mesh medicine.disease Hernia Ventral Surgery Treatment Outcome 030220 oncology & carcinogenesis Seroma Cohort Quality of Life Median body Female business Abdominal surgery |
| Zdroj: | Surgical endoscopy. 32(4) |
| ISSN: | 1432-2218 |
| Popis: | Biomaterial research has made available a biologically derived fully resorbable poly-4-hydroxybutyrate (P4HB) mesh for use in ventral and incisional hernia repair (VIHR). This study evaluates outcomes of patients undergoing VIHR with P4HB mesh. An IRB-approved prospective pilot study was conducted to assess clinical and quality of life (QOL) outcomes for patients undergoing VIHR with P4HB mesh. Perioperative characteristics were defined. Clinical outcomes, employment status, QOL using 12-item short form survey (SF-12), and pain assessments were followed for 24 months postoperatively. 31 patients underwent VIHR with bioresorbable mesh via a Rives–Stoppa approach with retrorectus mesh placement. The median patient age was 52 years, median body mass index was 33 kg/m2, and just over half of the patients were female. Surgical site occurrences occurred in 19% of patients, most of which were seroma. Hernia recurrence rate was 0% (median follow-up = 414 days). Patients had significantly improved QOL at 24 months compared to baseline for SF-12 physical component summary and role emotional (p |
| Databáze: | OpenAIRE |
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