Cintigrafía tiroidea (CT) con Tc99m- pertecnectato en recién nacidos (RN) con hipotiroidismo congénito (HC)
| Autor: | Carlos Becerra F, Gilda Donoso R, Francisca Arnello V, César Jiménez J, Bernardo Bruggendieck M, David Ladrón de Guevara H, Ximena Vivanco W, Gabriel Lobo S, Andrés Pérez R, María Eliana Bustos M, Jorge Brantes M |
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| Jazyk: | Spanish; Castilian |
| Rok vydání: | 2003 |
| Předmět: |
Newborn screening
medicine.medical_specialty Goiter Pertechnetate business.industry General Medicine medicine.disease Thyroid dysgenesis Gastroenterology Congenital hypothyroidism chemistry.chemical_compound Endocrinology Cretinism chemistry Hypothyroidism Internal medicine Myxedema medicine Etiology Endocrine system business Radionuclide Imaging Hormone |
| Zdroj: | Revista médica de Chile, Volume: 131, Issue: 3, Pages: 283-289, Published: MAR 2003 Revista médica de Chile v.131 n.3 2003 SciELO Chile CONICYT Chile instacron:CONICYT |
| Popis: | Background: Congenital hypothyroidism is one of the most frequent endocrine diseases of the newborn and requires an early diagnosis to avoid its deleterious effects on neurological and intellectual functions. Aim: To evaluate thyroid scintigraphy (TS) findings in newborns with congenital hypothyroidism (CH), detected in the national program of newborn screening, which is working in Chile since 1992. Material and methods: TS findings of 189 newborns with CH (68% female) were analyzed. Tc99m pertechnetate TS was performed at 19 ± 11 days of life. The gland was classified as eutopic, ectopic or absence of contrast (AC). Eutopic glands were classified by visual and quantitative criteria as: normal, goiter and decreased contrast (DC). TS results were compared by gender and hormonal levels. Results: Forty seven percent of newborns had ectopy, 29.1% eutopy and 24.3% AC. Eutopic gland predominated in males (44.2% vs 22.7%) and ectopy was more frequent in girls (53.1% vs 32.8%, p |
| Databáze: | OpenAIRE |
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