Skin prick test results to artesunate in children sensitized to Artemisia vulgaris L
| Autor: | Stefano Pantano, Luisa Galli, M. De Martino, Maria Elisabetta Rossi, Elena Chiappini, Elio Novembre, Carlotta Montagnani, Francesca Mori |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Intoxicative inhalant Adolescent Immunology Artemisia annua Artesunate Artemisia vulgaris L Pharmacology medicine.disease_cause chemistry.chemical_compound Allergen Hypersensitivity medicine Humans Immunology and Allergy Child Sensitization Skin Tests Artemisia vulgaris biology Traditional medicine business.industry Infant food and beverages Skin test Allergens biology.organism_classification Artemisinins medicine.anatomical_structure Artemisia chemistry Child Preschool Female business |
| Zdroj: | International Journal of Immunopathology and Pharmacology. 28:411-414 |
| ISSN: | 2058-7384 0394-6320 |
| DOI: | 10.1177/0394632015589518 |
| Popis: | Artemisia vulgaris L and Artemisia annua L (Chinese: qinghao) are similar plants of the Asterbaceae family. Artesunate, a semi-synthetic derivate of artemisin which is the active principle extract of the plant qinghao, has antimalarial properties. Some cases of severe allergic reactions to artesunate have been described. The purpose of this study was to evaluate the association between positive skin tests to Artemisia vulgaris L allergen and a preparation of injectable artesunate. A total of 531 children were skin prick tested with inhalants (including Artemisia vulgaris L), foods, and artesunate. Among the 59 patients positive to Artemisia vulgaris L only one child was also positive to artesunate. No child was positive to artesunate in those negative to Artemisia vulgaris L. We conclude that Artemisia vulgaris L sensitization is not associated with sensitization to artesunate; consequently, skin test to artesunate should not be carried out before using the drug considering the rare allergic reactions. |
| Databáze: | OpenAIRE |
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