Platelet lysate: a promising candidate in regenerative medicine
| Autor: | Ramin Pourakbari, Vafa Meftahpour, Ali Fotouhi, Ali Aghebati-Maleki, Leili Aghebati-Maleki, Amir Baghbanzadeh, Somaiyeh Malekghasemi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Blood Platelets
0303 health sciences Embryology business.industry Regeneration (biology) Mesenchymal stem cell Cell- and Tissue-Based Therapy Biomedical Engineering Mesenchymal Stem Cells Regenerative Medicine Regenerative medicine Cell therapy 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Cancer research Humans Intercellular Signaling Peptides and Proteins Medicine Platelet Platelet lysate business Bone regeneration Wound healing 030304 developmental biology |
| Zdroj: | Regenerative Medicine. 16:71-85 |
| ISSN: | 1746-076X 1746-0751 |
| DOI: | 10.2217/rme-2020-0065 |
| Popis: | Human platelet lysate has attracted much interest from many researchers as it is growth-factor rich for cell expansion, which is employed as a new therapeutic strategy. Not only are human platelet lysates used for cell therapy, but they are also used for the completion of basal media in mesenchymal stem cell cultures. Due to the presence of a large number of growth factors, platelet lysates have potential roles in wound healing, treatment of ocular graft-versus-host disease, osteoarthritis, Parkinson’s disease, tendon regeneration, infertility, androgenetic alopecia, nerve repair and regenerative tissue, such as bone regeneration. In this review, we summarize that platelet lysates could be valuable candidates for the treatment of a variety of diseases in regenerative medicine. |
| Databáze: | OpenAIRE |
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