Socioeconomic status and risk of incident venous thromboembolism
| Autor: | Sigrid Kufaas Brækkan, Henrik Toft Sørensen, Kristina Laugesen, Erzsébet Horváth-Puhó, Helle Jørgensen, John-Bjarne Hansen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Hematology: 775
VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Hematologi: 775 venous thromboembolism Danish socioeconomic status Risk Factors Odds Ratio Humans Medicine cardiovascular diseases Socioeconomic status education business.industry Incidence Incidence (epidemiology) Venous Thromboembolism Hematology Odds ratio Confidence interval language.human_language income Social Class employment language Conditional logistic regression business Venous thromboembolism Demography |
| Zdroj: | Jørgensen, H, Horváth-Puhó, E, Laugesen, K, Braekkan, S K, Hansen, J-B & Sørensen, H T 2021, ' Socioeconomic status and risk of incident venous thromboembolism ', Journal of Thrombosis and Haemostasis, vol. 19, no. 12, pp. 3051-3061 . https://doi.org/10.1111/jth.15523 |
| DOI: | 10.1111/jth.15523 |
| Popis: | Background: Although venous thromboembolism (VTE) is a leading cause of morbidity and mortality, and socioeconomic status (SES) affects human health and health behavior, few studies have examined the association between SES and VTE. Objectives: We aimed to investigate the association between SES, assessed individually and in a composite score by levels of education, income, and employment status, and incident VTE. Methods: We used Danish national registries to identify 51 350 persons aged 25– 65 years with incident VTE during 1995–2016. For each case, we used incidence density sampling to select five age-, sex-, and index-year-matched controls from the general Danish population (n = 256 750). SES indicators, including education, income, and employment status, were assessed 1 and 5 years before the VTE. We used conditional logistic regression to compute odds ratios (ORs) with 95% confidence intervals (CIs) for VTE according to individual SES indicators and a composite SES score in analyses adjusted for age, sex, and comorbidities. Results: Compared with low levels, high educational level (OR 0.74; 95% CI 0.71– 0.77), high income (OR 0.70; 95% CI 0.68–0.72), and high employment status (OR 0.66; 95% CI 0.64–0.68) were associated with decreased risk of VTE, even after adjusting for comorbidities. A composite SES score was superior to the individual indicators in assessing VTE risk (OR for high vs. low score: 0.61; 95% CI 0.59–0.63). In sensitivity analysis with SES indicators measured 5 years before the VTE, the risk estimates remained essentially the same. Conclusion: High levels of both individual SES indicators and a composite SES score were associated with decreased VTE risk. |
| Databáze: | OpenAIRE |
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