Impact of asthma on endoscopic sinus surgery outcomes for chronic rhinosinusitis with polyposis - A cohort study
| Autor: | Youssef Oukessou, Mohammed Roubal, Mohammed Laachoubi, Sami Rouadi, Meryem Lahjaouj, Khadija El Bouhmadi, Reda Abada, Mohammed Mahtar |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Population Disease 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine Medicine FESS education Cohort Study Asthma Nasal polyposis education.field_of_study Aspirin business.industry Public health SNOT 22 Retrospective cohort study General Medicine medicine.disease 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery business Cohort study medicine.drug |
| Zdroj: | Annals of Medicine and Surgery |
| ISSN: | 2049-0801 |
| DOI: | 10.1016/j.amsu.2021.102386 |
| Popis: | Introduction Chronic rhinosinusitis with polyposis (CRSwNP) is a multifactorial naso-sinusal inflammatory disease that affects 2–4% of the adult population. It highly affects the patient quality of life (QoL) in many levels making it a public health issue. The management of CRSwNP is based on a detailed clinical history, a complete endoscopic examination and a precise computed tomographic (CT) analysis. The aim of this study is to evaluate the prevalence and severity of the various CRS clinical manifestations as well as to highlight the potential relationship between symptom scores, asthma and ESS outcomes. Patients and methods A retrospective cohort study was performed in the 20 August hospital, between January 2017 and December 2018, on patients diagnosed with CRS according to guidelines recommendations, and were beforehand refractory to initial medical therapy and elected to FESS. The patients were divided into two groups, the first group (G1) of patients with asthma and the second (G2) without asthma in order to expose an eventual significant difference in the improvement of symptoms after surgery. The Sino Nasal Outcome Test-22 (SNOT-22) was used to evaluate QOL. Results A total of 100 patients participated in the study with an average age of 44.53 years. The sex ratio was 1.04 (51% men). Asthma was present in 48% of patients while 20% of patients were intolerant to aspirin with a significant difference between the asthmatic and non-asthmatic group (p 0.05). A higher significant improvement was observed between preoperative and postoperative SNOT-22 scores in group with asthma [42.7 ± 16.3 versus 11.8 ± 9.1] and in group without asthma [38.3 ± 15.1 versus 10.5 ± 14.2]. Conclusion Asthma in CRS is an additional symptom in these patients, mainly reflected in the subset of nasal symptoms in SNOT-22. However, it did not significantly affect the quality of life of the CRSwNP population. Highlights • Chronic rhinosinusitis with polyposis highly affects the patient quality of life in many levels making it a public health issue. • The aim of this study is to highlight the potential relationship between symptom scores, asthma and ESS outcomes. • SNOT-22 scores were significantly reduced in the postoperative period in the asthma and non-asthma groups, with no significant difference between the 2 groups. |
| Databáze: | OpenAIRE |
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