Dermatological and Genital Manifestations of Lyme Disease Including Morgellons Disease
| Autor: | Iris Du Cruz, Melissa C Fesler, Julie Lewis, John S Haggblad, Roberto M Martinez, Gilles A. Robichaud, Raphael B. Stricker, Marianne J Middelveen, Jyotsna S Shah |
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| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Case Report Dermatology Lymphocytic Infiltrate Lesion 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Lyme disease Borrelia tickborne disease Medicine Morgellons Disease spirochetes Borrelia burgdorferi erythema migrans biology business.industry bacterial infections and mycoses biology.organism_classification medicine.disease Rash 030220 oncology & carcinogenesis Erythema migrans medicine.symptom business Morgellons disease |
| Zdroj: | Clinical, Cosmetic and Investigational Dermatology |
| ISSN: | 1178-7015 |
| DOI: | 10.2147/ccid.s299526 |
| Popis: | Although the erythema migrans (EM) skin rash is traditionally considered a hallmark of Lyme disease, other dermatological manifestations of the tickborne disease are less well known. We describe a 49-year-old woman with erosive genital ulcerations, secondary EM rashes and jagged skin lesions associated with Lyme disease. The skin rashes exhibited fibers characteristic of Morgellons disease. Molecular testing confirmed the presence of Borrelia DNA in both vaginal culture and serum specimens. In further studies on a secondary EM lesion containing filaments, Gömöri trichrome staining revealed the presence of collagen in the filaments, while Dieterle and anti-Borrelia immunostaining revealed intracellular and extracellular Borrelia organisms. Intracellular staining for Borrelia was also observed in lymphocytic infiltrates. Lyme disease may present with a variety of genital lesions and dermatological manifestations including Morgellons disease. Careful evaluation is required to determine the presence of Borrelia organisms associated with these dermopathies. |
| Databáze: | OpenAIRE |
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