A Rare Cause of Thrombotic Thrombocytopenia Purpura- (TTP-) Like Syndrome, Vitamin B12 Deficiency: Interpretation of Significant Pathological Findings

Autor:	Robert Betancourt, Hani M. Babiker, Morgan Bailey, Dalia Mikhael, Travis Maestas
Rok vydání:	2019
Předmět:	Pediatrics medicine.medical_specialty lcsh:RC633-647.5 business.industry medicine.medical_treatment Case Report lcsh:Diseases of the blood and blood-forming organs General Medicine 030204 cardiovascular system & hematology medicine.disease Pancytopenia ADAMTS13 Rapid assessment 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Etiology Medicine Plasmapheresis 030212 general & internal medicine Vitamin B12 THROMBOCYTOPENIA PURPURA business Pathological
Zdroj:	Case Reports in Hematology, Vol 2019 (2019) Case Reports in Hematology
ISSN:	2090-6579 2090-6560
DOI:	10.1155/2019/1529306
Popis:	Thrombotic thrombocytopenia purpura (TTP) is a hematological emergency that requires rapid assessment followed by prompt initiation of therapy due to high mortality associated with delayed treatment. TTP has many causes including heritable syndromes, ADAMTS13 deficiency, and drugs-related etiologies. Profound vitamin B12 deficiency can, in rare cases, mimic TTP in presentation, and since plasmapheresis can be of limited benefit, prompt diagnosis is necessary for accurate treatment with B12. Therefore, careful analysis of all clinical signs, symptoms, and labs must be assessed. We report a patient who presented with a diagnosis of TTP, and repeat assessment confirmed a diagnosis of sever vitamin B12 (B12) deficiency with pancytopenia who was appropriately treated with B12.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b7b1b7ddb1758f75a8ec5cf179ab11 https://doi.org/10.1155/2019/1529306 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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