Supplementary Tables S1 - S5, Figures S1 - S5 from A Large Multiethnic Genome-Wide Association Study of Prostate Cancer Identifies Novel Risk Variants and Substantial Ethnic Differences

Autor: John S. Witte, Neil Risch, Catherine Schaefer, Pui-Yan Kwok, Mark N. Kvale, Daniela Seminara, Brian E. Henderson, Christopher A. Haiman, Lorelei A. Mucci, Kathryn L. Penney, Matthew L. Freedman, Qiyuan Li, Stephen N. Thibodeau, Daniel J. Schaid, Amy J. French, Shannon K. McDonnell, Stephen J. Chanock, Sonja I. Berndt, Zhaoming Wang, Joseph Presti, David Aaronson, Charles P. Quesenberry, Dilrini K. Ranatunga, Jun Shan, Nirupa R. Ghai, Chun R. Chao, Nima C. Emami, Clinton L. Cario, Michael N. Passarelli, Rebecca E. Graff, Laurel A. Habel, Eric Jorgenson, Lori C. Sakoda, Stephen K. Van Den Eeden, Thomas J. Hoffmann
Rok vydání: 2023
Popis: Supplementary Table S1. Descriptive factors for KP study population, broken down by study. Supplementary Table S2. Genome-wide significant SNPs found in our cohort. Supplementary Table S3. Cis-eQTL expression of rs4646284. Supplementary Table S4. Results at the 105 loci previously found to be associated with prostate cancer. Supplementary Table S5. Risk score of and variance explained by the 105 previously reported hits. Supplementary Figure S1. Manhattan and Q-Q plots of each race/ethnicity and meta-analysis. Supplementary Figure S2. Local plots of novel replicated rs4646284 and suggestive rs2659124. Supplementary Figure S3. Cis-eQTL of SLC22A1 and SLC22A3. Supplementary Figure S4. Comparison of ORs of KP to previous reports by race/ethnicity. Supplementary Figure S5. KP AUC estimates.
Databáze: OpenAIRE