Chrysiasis: Gold Aggregates Around a Nevus and Osteoma Cutis
Autor: | Binh Ngo, Brandon E. Cohen, Vignesh Ravi, Soma Sanyal, Jerrold L. Abraham, Gene Kim, Danielle Tran |
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Rok vydání: | 2021 |
Předmět: |
medicine.medical_specialty
Skin Neoplasms Dermatology Pathology and Forensic Medicine Arthritis Rheumatoid Gold injections Hyperpigmentation Humans Medicine Nevus Osteoma cutis skin and connective tissue diseases Aurothioglucose Nevus Pigmented business.industry Ossification Heterotopic Skin Diseases Genetic General Medicine Middle Aged Melanocytic nevus medicine.disease Chrysiasis Bone Diseases Metabolic Antirheumatic Agents Rheumatoid arthritis Female Gold medicine.symptom business Facial Dermatoses |
Zdroj: | The American Journal of Dermatopathology. 43:579-582 |
ISSN: | 0193-1091 |
DOI: | 10.1097/dad.0000000000001967 |
Popis: | Parenteral gold has historically been used to treat several conditions, including rheumatoid arthritis. Gold administration leads to a variety of cutaneous reactions, including chrysiasis, which is a permanent blue-grey hyperpigmentation of the skin due to dermal gold deposition. In this report, we describe the case of a patient who received parenteral gold injections 22 years before the onset of her chrysiasis for the treatment of rheumatoid arthritis. Biopsy of the macules showed dermal gold deposits aggregating around a melanocytic nevus, as well as around preexisting osteoma cutis. To the authors' knowledge, this is the first report in the literature describing a case of chrysiasis with gold deposits concentrated around a melanocytic nevus and an area of osteoma cutis. |
Databáze: | OpenAIRE |
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