Chrysiasis: Gold Aggregates Around a Nevus and Osteoma Cutis

Autor: Binh Ngo, Brandon E. Cohen, Vignesh Ravi, Soma Sanyal, Jerrold L. Abraham, Gene Kim, Danielle Tran
Rok vydání: 2021
Předmět:
Zdroj: The American Journal of Dermatopathology. 43:579-582
ISSN: 0193-1091
DOI: 10.1097/dad.0000000000001967
Popis: Parenteral gold has historically been used to treat several conditions, including rheumatoid arthritis. Gold administration leads to a variety of cutaneous reactions, including chrysiasis, which is a permanent blue-grey hyperpigmentation of the skin due to dermal gold deposition. In this report, we describe the case of a patient who received parenteral gold injections 22 years before the onset of her chrysiasis for the treatment of rheumatoid arthritis. Biopsy of the macules showed dermal gold deposits aggregating around a melanocytic nevus, as well as around preexisting osteoma cutis. To the authors' knowledge, this is the first report in the literature describing a case of chrysiasis with gold deposits concentrated around a melanocytic nevus and an area of osteoma cutis.
Databáze: OpenAIRE