An NNN-Pincer-Cobalt Complex Catalyzed Highly Markovnikov-Selective Alkyne Hydrosilylation
| Autor: | Jessica Juweriah Ibrahim, Yong Yang, Shaochun Zhang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
chemistry.chemical_classification
010405 organic chemistry Chemistry Hydrosilylation Organic Chemistry Markovnikov's rule Alkyne chemistry.chemical_element Regioselectivity 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences Catalysis Pincer movement chemistry.chemical_compound Physical and Theoretical Chemistry Cobalt |
| Zdroj: | Organic Letters. 20:6265-6269 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | A new NNN pincer (amine–pyridine–imine, API) cobalt complex, which is bench-stable and is applicable for the highly efficient and regioselective hydrosilylation of terminal alkynes, is developed. A broad set of α-vinylsilanes was successfully synthesized in good to high yields with up to 98/2 Markovnikov regioselectivity. This protocol can be readily scaled up for gram-scale synthesis and demonstrates the most efficient cobalt-catalyzed hydrosilylation of alkynes with turnover frequencies as high as 126 720 h–1 to date. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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