Perception of whole-body motion during balance perturbations is impaired in Parkinson's disease and is associated with balance impairment
| Autor: | Sistania M. Bong, Stewart A. Factor, Lena H. Ting, J. Lucas McKay |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Clinical variables Parkinson's disease media_common.quotation_subject Movement Biophysics Perturbation (astronomy) Poison control Audiology Article 03 medical and health sciences 0302 clinical medicine Perception Injury prevention Medicine Humans Orthopedics and Sports Medicine Postural Balance 030304 developmental biology media_common Aged 0303 health sciences Two-alternative forced choice business.industry Impaired Balance Healthy population Rehabilitation Parkinson Disease 030229 sport sciences Middle Aged medicine.disease Cross-Sectional Studies Female business Whole body Balance impairment 030217 neurology & neurosurgery Neurotypical |
| Zdroj: | Gait Posture |
| ISSN: | 1879-2219 |
| Popis: | BackgroundIn addition to motor deficits, Parkinson’s disease (PD) may cause perceptual impairments. The role of perceptual impairments in sensorimotor function is unclear, and has typically been studied in single-joint motions. Research Question: We hypothesized that perception of whole-body motion is impaired in PD and contributes to balance impairments. We tested 1) whether directional acuity to whole body perturbations during standing was worse in people with PD compared to neurotypical older adults (NOA), and 2) whether balance ability, as assessed by the MiniBESTest, was associated with poor directional acuity in either group.MethodsParticipants were exposed to pairs of support-surface translation perturbations in a two-alternative forced choice testing paradigm developed previously in a young healthy population. The first perturbation of each pair was directly backward and the second deviated to the left or right (1°–44°). Participants judged and reported whether the perturbations in each pair were in the “same” or “different” direction. This information was used to calculate directional acuity thresholds corresponding to “just-noticeable differences” in perturbation direction. Linear mixed models determined associations between directional thresholds and clinical variables including MDS UPDRS-III score, age, and MiniBESTest score. Results: 20 PD (64±7 y, 12 male, ⩾12 hours since last intake of antiparkinsonian medications) and 12 NOA (64±8, 6 male) were assessed. Directional thresholds were higher (worse) among PD participants (17.6±5.9° vs. 12.8±3.3°, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect