Plasma α-atrial natriuretic peptide concentrations in acute respiratory failure associated with sepsis
| Autor: | Chieko Mitaka, Yukjo Tsunoda, Hidenori Toyooka, Nobue Sakanishi, Takashi Nagura |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Blood Pressure Pulmonary Artery Critical Care and Intensive Care Medicine Sepsis Atrial natriuretic peptide medicine.artery Internal medicine medicine Natriuretic peptide Humans Alpha-Atrial Natriuretic Peptide Aged Aged 80 and over business.industry Respiratory disease Middle Aged medicine.disease Respiration Artificial Endocrinology medicine.anatomical_structure Respiratory failure Pulmonary artery cardiovascular system Vascular resistance Cardiology Vascular Resistance Respiratory Insufficiency business Atrial Natriuretic Factor hormones hormone substitutes and hormone antagonists |
| Zdroj: | Critical Care Medicine. 18:1201-1203 |
| ISSN: | 0090-3493 |
| DOI: | 10.1097/00003246-199011000-00002 |
| Popis: | Plasma alpha-atrial natriuretic peptide (alpha-ANP) concentrations were measured during mechanical ventilation in nine patients with acute respiratory failure (ARF) associated with sepsis. The relationships between alpha-ANP and pulmonary hemodynamic variables were examined. A total of 22 measurements of alpha-ANP and other variables were obtained. The mean plasma alpha-ANP concentration of 22 measurements was 120.1 +/- 79.8 pg/ml (normal 31.7 +/- 12.0, mean +/- SD). Plasma alpha-ANP concentrations correlated with mean pulmonary artery pressure (MPAP) (r = .703, p less than .01) and pulmonary vascular resistance (PVR) (r = .606, p less than .01), but not with other variables. These findings suggest that alpha-ANP elevation may be related to the increases in MPAP and PVR in ARF associated with sepsis. |
| Databáze: | OpenAIRE |
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