Failure of syndromic management due to drug-resistant Mycoplasma genitalium infection in South Africa: a case report

Autor: Jolein Laumen, Remco P. H. Peters, Oscar Radebe, Liteboho Daniel Maduna, Marleen M. Kock
Přispěvatelé: Promovendi PHPC, MUMC+: DA MMI Staf (9), RS: CAPHRI - R4 - Health Inequities and Societal Participation
Rok vydání: 2019
Předmět:
Male
Non-gonococcal urethritis
Mycoplasma genitalium
Drug resistance
Quinolones
0302 clinical medicine
Drug Resistance
Multiple
Bacterial
Pharmacology (medical)
030212 general & internal medicine
0303 health sciences
biology
treatment
Quinolone
Anti-Bacterial Agents
RNA
Ribosomal
23S
Infectious Diseases
Syndromic management
Macrolides
location
Adult
DNA
Bacterial
medicine.drug_class
men
Dermatology
Real-Time Polymerase Chain Reaction
03 medical and health sciences
23S ribosomal RNA
Dysuria
HIV Seronegativity
medicine
Humans
Urethritis
Mycoplasma Infections
Bacterial disease
030306 microbiology
business.industry
Public Health
Environmental and Occupational Health
other
Sequence Analysis
DNA
medicine.disease
biology.organism_classification
Virology
bacterial disease
Africa
Lost to Follow-Up
business
urethritis (bacterial)
Zdroj: International Journal of Std & Aids, 30(5), 519-521. SAGE Publications Ltd
ISSN: 1758-1052
0956-4624
Popis: We report a case of management failure of male urethritis syndrome due to macrolide-resistant Mycoplasma genitalium in South Africa. We detected mutations in 23S rRNA and one of the quinolone resistance-determining regions. This report confirms that drug-resistant M. genitalium infection can undermine the effectiveness of syndromic management in Africa.
Databáze: OpenAIRE
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