Excision of Granulation Tissue and Free Conjunctival Autograft in the Management of Necrotizing Scleritis
| Autor: | Clifford R. Weir, Kanna Ramaesh, Maria Elena Gregory |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Male
medicine.medical_specialty Conjunctiva Necrosis genetic structures medicine.medical_treatment Ophthalmologic Surgical Procedures Transplantation Autologous Young Adult Postoperative Complications Humans Medicine Potential source Necrotizing scleritis business.industry Granulation tissue Immunosuppression eye diseases Surgery Sclera Scleral melt Ophthalmology medicine.anatomical_structure Granulation Tissue Exotropia sense organs medicine.symptom business Scleritis |
| Zdroj: | Cornea. 29:577-579 |
| ISSN: | 0277-3740 |
| DOI: | 10.1097/ico.0b013e3181b532e5 |
| Popis: | PURPOSE To describe a novel use of conjunctival autograft in the management of surgically induced scleral necrosis that occurred after squint surgery. METHODS Interventional case report. RESULTS A 22-year-old man underwent bilateral adjustable squint surgery. Two weeks postoperatively, he developed conjunctival retraction and an area of scleral necrosis/melting with 80% thinning. The surrounding conjunctiva was markedly inflamed with raised edges. Screening for autoimmune and vasculitic conditions did not provide any positive results. The conjunctiva surrounding the area of scleral melt was excised and the area covered by a conjunctival autograft resulting in complete healing of the scleral melt within 1 month of surgery. CONCLUSION The pathogenesis of surgically induced scleral necrosis not associated with autoimmune conditions may be the result of the products of inflammation and lytic enzymes released by the surrounding conjunctival tissue initiating the scleral melting process. This type of surgically induced scleral necrosis may be successfully managed by excision of the surrounding inflamed conjunctiva, thus removing a potential source of collagenases, and covering the exposed sclera by a conjunctival transplant obviating the need for prolonged high-dose immunosuppression. |
| Databáze: | OpenAIRE |
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