Kepone-Induced Scoliosis and Its Histological Consequences in Fish
| Autor: | Larry R. Goodman, John A. Couch, James T. Winstead |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Nervous system
Insecticides medicine.medical_specialty Time Factors Central nervous system Hemorrhage Scoliosis Fish Diseases chemistry.chemical_compound Internal medicine medicine Animals Clinical syndrome Multidisciplinary Dose-Response Relationship Drug biology Intramuscular hemorrhage Muscles Fishes Sheepshead minnow biology.organism_classification medicine.disease Spine medicine.anatomical_structure Endocrinology chemistry Chlordecone Kepone Fish Calcium Muscle Contraction |
| Zdroj: | Science. 197:585-587 |
| ISSN: | 1095-9203 0036-8075 |
| Popis: | Scoliosis in fish is caused by several diverse agents that possibly act on the central nervous system, neuromuscular junctions, or ionic metabolism. The organochlorine pesticide Kepone induces scoliosis in the sheepshead minnow. Some effects associated with Kepone-induced scoliosis in these fish are disruption of myotomal patterns, inter- and intramuscular hemorrhage, fractured centra of vertebrae, and death. The histological syndrome of Kepone poisoning in fish and the clinical syndrome in humans suggest that the nervous system is a primary target for Kepone and that scoliosis is a secondary effect of Kepone poisoning in fish. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|