Association between Type D personality and outcomes in patients with non-ischemic heart failure

Autor: Anna Margrethe Thøgersen, Ulrik M. Mogensen, Line L Olesen, Gunnar Gislason, Lars Køber, Jens Cosedis Nielsen, Lars Videbæk, Jens Jakob Thune, Susanne S. Pedersen, Johan S Bundgaard, Christian Torp-Pedersen, Jens Haarbo, Lauge Østergaard
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Bundgaard, J S, Østergaard, L, Gislason, G, Thune, J J, Nielsen, J C, Haarbo, J, Videbæk, L, Olesen, L L, Thøgersen, A M, Torp-Pedersen, C, Pedersen, S S, Køber, L & Mogensen, U M 2019, ' Association between Type D personality and outcomes in patients with non-ischemic heart failure ', Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, vol. 28, no. 11, pp. 2901-2908 . https://doi.org/10.1007/s11136-019-02241-6
Bundgaard, J S, Østergaard, L, Gislason, G, Thune, J J, Nielsen, J C, Haarbo, J, Videbæk, L, Olesen, L L, Thøgersen, A M, Torp-Pedersen, C, Pedersen, S S, Køber, L & Mogensen, U M 2019, ' Association between Type D personality and outcomes in patients with non-ischemic heart failure ', Quality of Life Research, vol. 28, no. 11, pp. 2901-2908 . https://doi.org/10.1007/s11136-019-02241-6
DOI: 10.1007/s11136-019-02241-6
Popis: PURPOSE: The "distressed" (Type D) personality trait has been reported to be over-represented in patients with heart failure (HF) compared to the background population and may provide prognostic information for mortality. We examined the association between Type D personality and outcomes in the DANISH trial (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators in Patients with Non-ischemic Systolic Heart Failure on Mortality).METHODS: The DANISH trial included a total of 1116 patients with non-ischemic HF on guideline-recommended therapy. Type D personality was assessed with the Type D Scale (DS14) at baseline and investigated through follow-up accordingly. Multivariable Cox proportional hazard models were used to compare hazard ratios (HR) of cardiovascular and all-cause mortality.RESULTS: Type D personality assessment was completed by 873 (78%) patients at baseline and Type D personality was found in 120 (14%) patients. The median follow-up was 67 months (interquartile range [IQR] 48-83). Among patients with versus without Type D personality, 22% versus 19% died from all-cause yielding similar incidence rates of 4.62 (95% CI 3.14-6.87) versus 3.95 (95% CI 3.37-4.66) per 100 person-years. The adjusted risk of all-cause mortality was not significantly different in patients with versus without Type D personality with an adjusted HR of 1.31 (95% CI 0.84-2.03, p = 0.23) with similar results for cardiovascular death (HR 1.46 (95% CI 0.88-2.44, p = 0.15).CONCLUSION: Type D personality was not significantly associated with increased risk of all-cause mortality or cardiovascular death in patients with non-ischemic HF.
Databáze: OpenAIRE