The effect of hemoperfusion on patients with toxic encephalopathy induced by silkworm chrysalis ingestion
| Autor: | Xiao-Liang Liu, Jing Sun, Hai-Xia Hu, Jihong Xing, Jiaqi Lv, Xu Wang |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male 0106 biological sciences medicine.medical_specialty medicine.medical_treatment Neurological examination 01 natural sciences Gastroenterology Foodborne Diseases Eating 03 medical and health sciences 0302 clinical medicine Furosemide 030225 pediatrics Internal medicine medicine Animals Humans Ingestion Diuretics Omeprazole Aged medicine.diagnostic_test Vitamin C business.industry Therapeutic effect Pupa Toxic encephalopathy Proton Pump Inhibitors General Medicine Middle Aged Bombyx Hemoperfusion Calcium Gluconate Surgery 010602 entomology Treatment Outcome Fluid Therapy Female Neurotoxicity Syndromes business medicine.drug |
| Zdroj: | Scottish Medical Journal. 61:149-154 |
| ISSN: | 2045-6441 0036-9330 |
| DOI: | 10.1177/0036933015619291 |
| Popis: | This study aims to determine therapeutic effect of hemoperfusion on patients with acute toxic encephalopathy induced by silkworm chrysalis ingestion. Three patients who developed toxic encephalopathy after chrysalis ingestion were analysed. Two patients lost their consciousness, while two patients had typical extrapyramidal tremor symptoms. Further neurological examination revealed various degrees of muscle strength impairment in these patients. All of them received treatments of omeprazole (40 mg/day), furosemide (one dose of 20 mg), vitamin C (2.0 g/day), calcium gluconate (2.0 g/day) and rehydration with glucose and sodium chloride (1500 ml/day). In addition, they received hemoperfusion treatment for 1.5 h. All patients recovered well after hemoperfusion. Two patients with loss of consciousness significantly recovered at 45 min and 65 min after hemoperfusion, respectively. All tremor symptoms were completely resolved in these patients at 30 min, 50 min, and 70 min following treatment, respectively. After the hemoperfusion treatment, encephalopathy symptoms of two patients had completely disappeared. All patients were followed up for one month and did not report any abnormalities. Our study indicates that hemoperfusion could be a useful and efficient treatment strategy for patients with acute encephalopathy after silkworm chrysalis ingestion. Larger clinical trials with longer follow-up are warranted to confirm the clinical benefit of hemoperfusion. |
| Databáze: | OpenAIRE |
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