Supplementary Data - Publication Only from The Hippo Pathway Component TAZ Promotes Immune Evasion in Human Cancer through PD-L1

Autor: Xiaolong Yang, Michael J. Rauh, Charles H. Graham, Lori M. Minassian, Prem Khanal, Brooke Snetsinger, Yawei Hao, Min Ling, Taha Azad, Helena J. Janse van Rensburg
Rok vydání: 2023
DOI: 10.1158/0008-5472.22421070
Popis: This file contains supplementary figures summarizing control experiments that support conclusions from the main text. Figure S1: Candidates from our NanoString screen are not upregulated due to EMT or doxycycline treatment. Figure S2: CYR61 mRNA expression is regulated by modulation of the Hippo pathway. Figure S3: Clinical datasets support a relationship between TAZ, YAP and PD-L1. Figure S4: Pd-l1, Pd-l2, S1pr1 and Nlrp3 are differentially regulated by YAP/TAZ in human and mouse cell lines. Figure S5: Candidates from our mouse NanoString screen are not upregulated due to doxycycline treatment. This file also contains Supplementary Methods.
Databáze: OpenAIRE