| Autor: |
April A.N. Rose, Peter M. Siegel, Ian R. Watson, Catalin Mihalcioiu, Kevin Petrecca, Marie-Christine Guiot, Morag Park, David Hogg, Dana Vuzman, Alexei Protopopov, Maria Lvova, Xiu Huang, Shivshankari Rajkumar, Paul Savage, Tan-Trieu Nguyen, Dan Moldoveanu, Mathieu Lajoie, Matthew Dankner |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1078-0432.22470735 |
| Popis: |
FIGURE S1: LY3009120 is an effective inhibitor of BRAF class II mutant melanoma cells. FIGURE S2: Bioinformatic characterization of PDX models. FIGURE S3: Inhibitory effects of BRAF and MEK inhibitors in melanoma cells. FIGURE S4: Representative images from cell growth clonogenic assays. FIGURE S5: Encorafenib and binimetinib are an effective combination for class II BRAF mutant melanoma. FIGURE S6: Dual MAPK inhibition slows progression of class II BRAF mutant melanoma brain metastases. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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