Synthesis and Antifungal Evaluation of Quaternary Ammonium Salts Derivatives of Dialkylaminoethyl Methacrylate Bearing 1,3,4-Oxadiazoles Moieties
| Autor: | Sofiane Daoudi, Tahar Benaissa, Nisserine Hamini-Kadar, Zahra Ould Kada |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Antifungal Fusarium biology medicine.drug_class Carbon-13 NMR Methacrylate biology.organism_classification Lauric acid 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology chemistry Fusarium oxysporum medicine Organic chemistry Ammonium Fusarium commune |
| Zdroj: | International Letters of Chemistry, Physics and Astronomy. 67:36-41 |
| ISSN: | 2299-3843 |
| DOI: | 10.18052/www.scipress.com/ilcpa.67.36 |
| Popis: | Starting from lauric acid two novel quaternary ammonium salts containing 1,3,4-Oxadiazoles nucleus derivative from N,N-Diethylaminoethyl Methacrylate (DEAEMA) and N,N-Dimethylaminoethyl Methacrylate (DMAEMA) was successfully synthesized and characterized by IR, 1H and 13C NMR, All the synthesized compounds were evaluated for their preliminary in vitro antifungal activity against three fungal strains such as Fusarium oxysporum, Fusarium commune and Fusarium rodelens. The synthesized compounds showed promising antifungal potential against the phytopathogenic test fungi. |
| Databáze: | OpenAIRE |
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