CARDIOVASCULAR FUNCTION IN EXTREME OBESITY
| Autor: | Ulla Freyschuss, Lars Bäckman, A. Melcher, Dag Hallberg |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Cardiac Catheterization medicine.medical_specialty Cardiac output Adolescent Cardiac Volume Physical Exertion Blood Pressure Blood volume Cardiovascular System Electrocardiography Hemoglobins Oxygen Consumption Heart Rate Internal medicine Heart rate Internal Medicine medicine Humans Obesity Cardiac Output Blood Volume business.industry Body Weight Hemodynamics Stroke volume Middle Aged Body Height Blood pressure medicine.anatomical_structure Anesthesia Circulatory system Exercise Test Vascular resistance Cardiology Female Vascular Resistance business |
| Zdroj: | Acta Medica Scandinavica. 193:437-446 |
| ISSN: | 0001-6101 |
| Popis: | Cardiovascular function in 19 patients with obesity has been studied by electrocardiography (ECG), exercise test, determination of heart and blood volumes, and right heart catheterization. Pathological ECG findings appeared in one patient at rest and during exercise, and in another only during exercise. Blood volume was low in relation to body weight, but hemoglobin concentration was normal. Heart volume and stroke volume were normally related to the total amount of hemoglobin (THb), while the working capacity (W170) in eight cases was low in relation to THb. The cardiac output was found to be normal when related to the oxygen intake both at rest and during exercise. There was a statistically significant linear relationship between intravascular pressures and cardiac output. Brachial artery pressures and left ventricle filling pressure were significantly elevated at rest and during exercise, while pulmonary artery pressures and end-diastolic pressure of the right ventricle showed a statistically significant steeper rise with increase in cardiac output than normally found. It is concluded that the circulatory dimensions and the cardiac output reflect an adequate adaptation to the metabolic demands laid upon the circulation in obesity. The elevated filling pressures of the ventricles and the high systemic and pulmonary vascular resistance, however, suggest that obesity is not without deleterious effect on cardiovascular function. |
| Databáze: | OpenAIRE |
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